<noframes id="bhbxf">

    <address id="bhbxf"></address>
    <sub id="bhbxf"></sub>
      <address id="bhbxf"></address>

      <address id="bhbxf"><address id="bhbxf"><menuitem id="bhbxf"></menuitem></address></address>

      <noframes id="bhbxf">
      當前位置:首頁 > 智慧健康列表 > 光生物學與技術 > 詳細信息
      智能磁共振成像造影劑的研究進展
      來源: | 作者: | 發布時間:2014-4-15 17:59:18

      智能磁共振成像造影劑的研究進展
      錢玉娥1,王天宇2,唐建斌2
      (1. 浙江大學醫學院附屬邵逸夫醫院放射科,杭州 310027;2. 浙江大學生物納米工程中心,化學工程與生物工程學系,杭州 310027)
      摘要:智能MRI 造影劑能夠對特定或者病變的一些信號如pH、金屬離子、酶、其他生物分子做出響應,改變其弛豫率。它們不僅能夠提高MRI 對病變的檢測靈敏度,而且能夠針對病變的信號分子進行分子成像。本項詳細綜述了pH、金屬離子、酶、其他生物分子等響應的智能造影劑,分析了他們的結構和響應機制及其應用前景,并對未來的研究方向做了展望。
      關鍵詞:磁共振成像;造影劑;釓配合物;疾病診斷
      中圖分類號:O6-1
      Research Progress in Smart MRI Contrast Agent
      Qian Yue1, Wang Tianyu2, Tang Jianbin2
      (1. Department of Radiology, Sir Run Run Shaw Hospital (SRRSH) of School of Medicine,Zhejiang University, HangZhou 310027;2. Department of Chemical and Biological Engineering, Center for Bioengineering, Zhejiang University, HangZhou 310027)
      Abstract: Smart magnetic resonance imaging (MRI) contrast agents change their relexivities upon the stimulus of pH, ion, enzyme and other biomolecules from specific or pathologic tissues. They not only improve the sensitivity of disease detection by MRI, but also make the molecular imaging of disease signal by MRI possible. This paper gives a review of smart MRI contrast agents responding to pH, ion, enzyme and other biomolecules with the focus on their structures,responding mechanism, and perspectives.
      Keywords: Magnetic resonance imaging; Contrast agent; Gadolinium complexes; Disease diagnosis

      256彩票 www.8816l.com | www.550424.com | www.755804.com | www.581166.com | www.177806.com | www.52303h.com | www.50026f.com | www.1368s.cc | www.638477.com | www.191061.com | www.91233k.com | www.2632v.com | www.c4520.com | www.560692.com | www.88266z.com | www.41518k.com | www.cp9829.com | www.452816.com | www.61233r.com | www.5086s.com | www.987434.com | www.508433.com | www.62118b.com | www.16001.com | www.fz34.com | www.196029.com | www.50026l.com | www.627012.com | www.178311.com | www.8667g.com | www.586960.com | www.29178a.com | www.9889hc.com | www.641638.com | www.51331a.com | www.9889hc.com | www.674679.com | www.39500u.com | www.9889hc.com | www.588824.com | www.77802h.com | www.354911.com | www.60123k.com | www.855271.com | www.52303i.com | www.rrle2.com | www.045445.com | www.102ak.com | www.330715.com | www.3478e.cc | www.218565.com | www.3890m.com | www.551416.com | www.36166b.com | www.511174.com | www.3478p.cc | www.36788e.com | www.768299.com | www.99638b.com | www.98528f.com | www.50024w.com | www.550437.com | www.3479c.com | www.65707s.com | www.970358.com | www.49956p.com | www.914979.com | www.81678m.com | www.54968f.com | www.528qx.com | www.003851.com | www.98528f.com | www.50080z.com | www.262072.com | www.839658.com | www.15355p.com | www.093388.com | www.776511.com | www.7782p.com | www.055520.cc | www.am6633.com | www.99849.cc | www.60007h.com | www.209703.com | www.868216.com | www.bxcp3333.com | www.32123i.com | www.345512.com | www.978797.com | www.9155h.cc | www.50732s.com | www.71233i.com | www.454589.com | www.941718.com | www.2934u.com | www.51515d.com | www.96386q.com | www.701574.com | www.18kpl.com | www.60007t.com | www.84499s.com | www.372839.com | www.925887.com | www.636by.com | www.71399l.com | www.61655w.com | www.391438.com | www.rcw456.com | www.927260.com | www.2875u.com | www.21202g.com | www.99677p.com | www.65707a.com | www.78700m.com | www.178725.com | www.399130.com | www.548611.com | www.591799.com | www.744343.com | www.799845.com | www.896950.com | www.936570.com | www.978960.com | www.c1353.com | www.957588.com | www.gai00.com | www.bxcp3333.com | www.ybao3.com | www.ywzuqiu.com | www.78wcp.com | www.hy5155.com | www.ya499.com | www.971261.com | www.768299.com | www.769301.com | www.538699.com | www.369053.com | www.106537.com | www.73736b.com | www.16878n.com | www.25688d.com | www.691063.com | www.390675.com | www.163910.com | www.52303z.com | www.35918p.com | www.2588cai.com | www.hcjt0.com | www.802190.com | www.530534.com | www.021037.com | www.88266p.com | www.2109a.com | www.aa0090.com | www.50788m.com | www.3416w.com | www.qucp5.com | www.767198.com | www.324177.com | www.66621o.com | www.29178h.com | www.tctx6.com | www.618477.com | www.68568c.com | www.33997r.com | www.912278.com | www.339219.com | www.99788s.com | www.8000hc.com | www.659957.com | www.86267f.com | www.7793x.com | www.cp3.mobi | www.83993f.com | www.25688k.com | www.767884.com | www.81233r.com | www.14392.com | www.177348.com | www.53168.com | www.755834.com | www.68568b.com | www.2875s.com | www.453552.com | www.66332t.com | www.961205.com | www.83993v.com | www.055aa.cc | www.84499s.com | www.080wy.com | www.330985.com | www.26163z.com | www.630565.com | www.80065z.com | www.669308.com | www.81678j.com | www.xinyc3.com | www.36787j.com | www.xinyc2.com | www.35918x.com | www.318548.com | www.53900p.com | www.88kcw.com | www.43131t.com | www.902261.com | www.08588g.com | www.730265.com | www.50064c.com | www.hcw332.com | www.9889hc.com | www.91233r.com | www.950633.com | www.90305b.com | www.597933.com | www.1368j.cc | www.15355q.com | www.570126.com | www.2373q.com | www.52072a.com | www.801896.com | www.35918f.com | www.399146.com | www.38wcp.com | www.33588r.com | www.hcw332.com | www.hx1111.com | www.50989g.com | www.197560.com | www.858776.com | www.8999ka.com | www.33112t.com | www.lcw199.com | www.890732.com | www.2109w.com | www.84499c.com | www.330732.com | www.910355.com | www.3478k.cc | www.73166h.com | www.xinyc8.com | www.732779.com | www.66kcw.com | www.50054b.com | www.281877.com | www.339968.com | www.669773.com | www.hc5859.com | www.022bj.cc | www.12455c.com | www.00665d.com | www.55558c.com | www.209213.com | www.541811.com | www.646959.com | www.949403.com | www.hczx4.com | www.062wy.com | www.6364x.com | www.68568l.com | www.50732h.com | www.99638p.com | www.233591.com | www.346918.com | www.508477.com | www.606643.com | www.730124.com | www.hcw332.com | www.965960.com | www.ck7786.com | www.zfcp2.com | www.076wy.com | www.983jc.com | www.1035i.com | www.3552p.com | www.5091l.com | www.072wy.com | www.fh7557.com | www.sxyl7.com | www.c229.com | www.560621.com | www.530861.com | www.385626.com | www.278206.com | www.186297.com | www.112559.com | www.83993y.com | www.50732o.com | www.96386n.com | www.49956c.com | www.8667o.com | www.65yb.com | www.lcw997.com | www.548511.com | www.88266y.com | www.81678x.com | www.1368v.cc | www.920564.com | www.627791.com | www.113438.com | www.08588e.com | www.099wy.com | www.694050.com | www.208990.com | www.26878y.com | www.8667s.com | www.901572.com | www.346377.com | www.99638g.com | www.8fk.com | www.628867.com | www.bxcp3.com | www.36166l.com | www.978797.com | www.367474.com | www.00665e.com | www.lu126.com | www.550419.com | www.55885c.com | www.1368n.cc | www.586775.com | www.60108k.com | www.277ak.com | www.66376w.com | www.982jc.com | www.401274.com | www.83993f.com | www.hr5888.com | www.le33.cc | www.49956q.com | www.906880.com | www.36788r.com | www.ch8922.com | www.131671.com | www.1368u.cc | www.160951.com | www.361gc.com | www.440689.com | www.35155f.com | www.703153.com | www.80065h.com | www.899465.com | www.43818f.com | www.331616a.com | www.77210k.com | www.c7268.com | www.77801v.com | www.hczx7.com | www.77996d.com | www.989569.com | www.35918u.com | www.756586.com | www.33598j.com | www.376817.com | www.004ac.com | www.97655g.com | www.c6078.com | www.50052i.com | www.867455.com | www.50064l.com | www.397760.com | www.66ffn.com | www.43818s.com | www.646959.com | www.5086q.com | www.040419.com | www.854277.com | www.9356f.com | www.87668z.com | www.858899.com | www.00840k.com | www.129989.com | www.907556.com | www.7782e.com | www.61233s.com | www.588703.com | www.2tdc.com | www.34788x.com | www.86267t.com | www.607217.com | www.hy5501.com | www.67767.cc | www.29178d.com | www.324377.com | www.695037.com | www.23040.com | www.50052f.com | www.76520y.com | www.374977.com | www.802190.com | www.8000hc.com | www.68689m.com | www.77803y.com | www.257630.com | www.hcw266.com | www.318548.com | www.8000hc.com | www.36788z.com | www.36788r.com | www.131671.com | www.375983.com | www.fh7557.com | www.978366.com | www.33qxc.com | www.5666hc.com | www.8839e.com | www.65707x.com | www.07163r.com | www.55558c.com | www.77114z.com | www.99677u.com | www.136031.com | www.265553.com | www.413552.com | www.xinyc8.com | www.583792.com | www.yc7701.com | www.602472.com | www.560723.com | www.551727.com | www.hcw332.com | www.506232.com | www.398118.com | www.303766.com | www.278202.com | www.193987.com | www.guocai667.com | www.024028.com | www.97655d.com | www.41518l.com | www.83993x.com | www.33997m.com | www.3890y.com | www.qlc3.com | www.799657.com | www.hcw332.com | www.hcw776.com | www.55228l.com | www.68689r.com | www.509866.com | www.ya238.com | www.lcw997.com | www.502433.com | www.88266o.com | www.88266j.com | www.5091d.com | www.c609.vip | www.364277.com | www.68689x.com | www.60108s.com | www.085wy.com | www.810730.com | www.223065.com | www.83993c.com | www.091wy.com | www.768399.com | www.197620.com | www.97655l.com | www.1555hc.com | www.675686.com | www.81233r.com | www.15355f.com | www.936399.com | www.224066.com | www.60007p.com | www.df76.com | www.132031.com | www.49956c.com | www.934077.com | www.127283.com | www.26878w.com | www.901187.com | www.90305f.com | www.3416m.com | www.wcp666888.com | www.50024a.com | www.05gcw.com | www.320663.com | www.08588q.com | www.622209.com | www.21202t.com | www.927035.com | www.51515j.com | www.hf5885.com | www.81520p.com | www.9155d.cc | www.607269.com | www.0014b.com | www.wcp777888.com | www.79520d.com | www.cpkk9.com | www.78700m.com | www.hx5577.com | www.60123c.com | www.992599.com | www.34788w.com | www.819920.com | www.86267n.com | www.669308.com | www.52303f.com | www.526051.com | www.3126t.com | www.106267.com | www.318548.com | www.36788o.com | www.629293.com | www.5688y.cc | www.71233b.com | www.810726.com | www.53539.cc | www.81678c.com | www.lcw997.com | www.14177.com | www.001865.com | www.tcp969.com | www.38396.com | www.99677d.com | www.799100.com | www.3668u.com | www.71233c.com | www.630675.com | www.267by.com | www.08588p.com | www.289379.com | www.901512.com | www.5086z.com | www.50074j.com | www.426689.com | www.938537.com | www.cll168.com | www.08588d.com | www.171880.com | www.694050.com | www.66yfa.com | www.35918g.com | www.76520i.com | www.423552.com | www.887575.com | www.bxcp3.com | www.08588m.com | www.35918o.com | www.029509.com | www.493326.com | www.809183.com | www.500106.com | www.798288.com | www.hy5755.com | www.1368q.cc | www.6832n.com | www.66332k.com | www.35918e.com | www.77210j.com | www.097067.com | www.203035.com | www.hcw332.com | www.583792.com | www.628987.com | www.723035.com | www.833314.com | www.283550.com | www.cai003.vip | www.hx1112.com | www.ybao9.com | www.sxyl4.com | www.yi328.com | www.zfcp1.com | www.jcai3.com | www.hr9888.com | www.318548.com | www.809215.com | www.842223.com | www.fh7557.com | www.599487.com | www.475711.com | www.302591.com | www.127918.com | www.84499b.com | www.50732u.com | www.23579f.com | www.50051d.com | www.870300.com | www.599748.com | www.375983.com | www.160592.com | www.54400b.com | www.77803m.com | www.5522o.cc | www.am5432.com | www.652392.com | www.302210.com | www.71399z.com | www.66652b.com | www.1368b.cc | www.wcp8008.com | www.133615.com | www.351871.com | www.84499n.com | www.99677d.com | www.cll168.com | www.qmkl9.com | www.701775.com | www.196095.com | www.29277b.com | www.3478n.cc | www.799100.com | www.243552.com | www.04500w.com | www.288hc.com | www.730631.com | www.106267.com | www.50080d.com | www.ac3177.com | www.509980.com | www.187397.com | www.60123r.com | www.qm26.com | www.296380.com | www.61233l.com | www.318548.com | www.196303.com | www.36166r.com | www.901068.com | www.bxcp3.com | www.781566.com | www.791571.com | www.83033c.com | www.5086m.com | www.606614.com | www.33588c.com | www.hc8878.com | www.113438.com | www.8499h.com | www.651012.com | www.07163b.com | www.975627.com | www.76520z.com | www.090.la | www.106560.com | www.084wy.com | www.267051.com | www.7782m.com | www.407869.com | www.90767.com | www.535350.com | www.08588d.com | www.532918.com | www.98255.com | www.luck808.com | www.781566.com | www.292199.com | www.977hf.com | www.96386d.com | www.hy6937.com | www.50732m.com | www.907844.com | www.80065k.com | www.605670.com | www.cll168.com | www.217302.com | www.lfu8.com | www.99001r.com | www.607219.com | www.9155h.cc | www.028082.com | www.987590.com | www.65707b.com | www.373170.com | www.077wy.com | www.39957d.com | www.599690.com | www.091wy.com | www.43131b.com | www.586960.com | www.8000hc.com | www.39500p.com | www.504833.com | www.flff9.com | www.65707q.com | www.128368.com | www.802865.com | www.2632y.com | www.34788h.com | www.507933.com | www.hf6880.com | www.25688m.com | www.83993i.com | www.594611.com | www.c189.vip | www.5086u.com | www.33598o.com | www.229075.com | www.fh7557.com | www.16wa.com | www.5522j.cc | www.77802m.com | www.80075i.com | www.376519.com | www.781367.com | www.bei05.com | www.9889hc.com | www.80075j.com | www.62118a.com | www.330175.com | www.621341.com | www.987426.com | www.061wy.com | www.8499c.com | www.78949b.com | www.73166g.com | www.186792.com | www.397730.com | www.606255.com | www.810612.com | www.979505.com | www.fh52.com | www.w931.com | www.622by.com | www.0014y.com | www.9356g.com | www.15355f.com | www.57578h.com | www.cpyz1.com | www.w593.com | www.ascp6.com | www.ascp4.com | www.sygj7.com | www.zfcp5.com | www.tctx2.com | www.hy5505.com | www.c177.com | www.912183.com | www.840689.com | www.631799.com | www.652331.com | www.583792.com | www.524277.com | www.xinyc5.com | www.003561.com | www.50788k.com | www.97655d.com | www.36787j.com | www.3890s.com | www.9889hc.com | www.gocp2.com | www.876747.com | www.592909.com | www.309135.com | www.77210e.com | www.07163z.com | www.67767.cc | www.ji224.com | www.870933.com | www.570126.com | www.178192.com | www.49956l.com | www.26163s.com | www.535hc.com | www.877719.com | www.433737.com | www.77802c.com | www.50052r.com | www.2kc.com | www.689044.com | www.djcp004.com | www.29178b.com | www.2875s.com | www.943893.com | www.346577.com | www.43131r.com | www.3933u.cc | www.805595.com | www.199207.com | www.78700h.com | www.ban03.com | www.22630.cc | www.17wsz.com | www.66652m.com | www.77802d.com | www.359500.com | www.50052m.com | www.3478q.cc | www.664628.com | www.81520p.com | www.8667d.com | www.764499.com | www.81520r.com | www.5095n.com | www.701250.com | www.65707x.com | www.66fft.com | www.362803.com | www.52303g.com | www.901021.com | www.73166c.com | www.55ckb.com | www.316477.com | www.36166t.com | www.810715.com | www.66376p.com | www.38y.com | www.176223.com | www.1035g.com | www.386918.com | www.99849.cc | www.yc7701.com | www.60108n.com | www.627012.com | www.77802l.com | www.722571.com | www.77801p.com | www.677474.com | www.77210j.com | www.710230.com | www.51515d.com | www.560926.com | www.24020.cc | www.293255.com | www.089c.cc | www.178562.com | www.fl96.com | www.50054t.com | www.821260.com | www.66653z.com | www.503489.com | www.23040.com | www.040416.com | www.hm8222.com | www.33598k.com | www.620557.com | www.3668w.com | www.109027.com | www.c3069.com | www.81520h.com | www.550154.com | www.126xc.com | www.49956f.com | www.591411.com | www.9889hc.com | www.39500j.com | www.533508.com | www.5xce.com | www.88858c.com | www.328477.com | www.gy11.com | www.15355f.com | www.95999w.com | www.607325.com | www.068wy.com | www.81233z.com | www.223085.com | www.910336.com | www.9928aa.com | www.00840d.com | www.193987.com | www.810277.com | www.091wy.com | www.50054y.com | www.81678p.com | www.498266.com | www.922069.com | www.9889hc.com | www.68568l.com | www.81520y.com | www.444627.com | www.xinyc3.com | www.gczj5.com | www.5095o.com | www.78700g.com | www.77114e.com | www.320477.com | www.bxcp3333.com | www.rcw8866.com | www.bxcp3333.com | www.33588b.com | www.15355n.com | www.77802w.com | www.237988.com | www.527990.com | www.781217.com | www.927633.com | www.ya088.com | www.8999ka.com | www.9356j.com | www.50051l.com | www.bxcp3.com | www.43131e.com | www.66376m.com | www.83993f.com | www.055983.com | www.196702.com | www.322918.com | www.dacp123.com | www.558424.com | www.591031.com | www.580820.com | www.535666e.com | www.901527.com | www.926730.com | www.872198.com | www.810877.com | www.290282.com | www.624880.com | www.548911.com | www.xcw866.com | www.302029.com | www.161172.com | www.81520x.com | www.50052a.com | www.80075j.com | www.50024r.com | www.9889hc.com | www.9889hc.com | www.23040.com | www.901021.com | www.606285.com | www.338062.com | www.106726.com | www.50080a.com | www.68689c.com | www.6661e.cc | www.gai50.com | www.911750.com | www.548477.com | www.102386.com | www.29277l.com | www.42969.com | www.23040.com | www.755860.com | www.319826.com | www.53900j.com | www.25688p.com | www.ya115.com | www.656121.com | www.278206.com | www.50026f.com | www.3005w.com | www.c5617.com | www.637012.com | www.92967a.com | www.41518d.com | www.slyl2.com | www.679957.com | www.99677e.com | www.39957b.com | www.c300.vip | www.357876.com | www.26299p.com | www.062wy.com | www.676944.com | www.71233s.com | www.3416g.com | www.98528f.com | www.73166j.com | www.2632o.com | www.669771.com | www.77803t.com | www.2632g.com | www.672766.com | www.51515t.com | www.069wy.com | www.399047.com | www.61655j.com | www.xinyc8.com | www.89894e.com | www.cp7777b.com | www.50732m.com | www.sjgc3.com | www.177417.com | www.2875s.com | www.506293.com | www.43818g.com | www.290282.com | www.36787h.com | www.ch8922.com | www.77803l.com | www.4dwj.com | www.001865.com | www.097wy.com | www.139670.com | www.bxcp3.com | www.186287.com | www.016ac.com | www.196303.com | www.002hy.cc | www.137105.com | www.500lian.com | www.022190.com | www.ybao9.com | www.65707j.com | www.guocai667.com | www.50052w.com | www.901068.com | www.81678m.com | www.606187.com | www.9478p.com | www.345512.com | www.070wy.com | www.83033x.com | www.54968f.com | www.77801m.com | www.455518.com | www.5666hc.com | www.66332t.com | www.769639.com | www.9478o.com | www.129985.com | www.983480.com | www.77114l.com | www.371477.com | www.ya466.com | www.85858hh.com | www.514211.com | www.ya618.com | www.07163c.com | www.372082.com | www.hy6933.com | www.50080h.com | www.191079.com | www.860958.com | www.6539x.com | www.66332v.com | www.54968f.com | www.6fk.com | www.60007j.com | www.068673.com | www.652699.com | www.44czt.com | www.68689n.com | www.101372.com | www.652912.com | www.ya160.com | www.36788h.com | www.81233h.com | www.526411.com | www.907712.com | www.9889hc.com | www.68568k.com | www.80075k.com | www.98528f.com | www.866509.com | www.6hcczz.com | www.9155f.com | www.91233c.com | www.88266p.com | www.351376.com | www.99djcp.com | www.c9220.com | www.022zj.cc | www.97171.cc | www.88266m.com | www.61233u.com | www.111307.com | www.363116.com | www.595411.com | www.775740.com | www.976506.com | www.gyfc2.com | www.288hc.com | www.3479b.com | www.08588t.com | www.60007f.com | www.bxcp3.com | www.33598n.com | www.77801q.com | www.028314.com | www.171109.com | www.197880.com | www.278207.com | www.276081.com | www.314877.com | www.346077.com | www.348689.com | www.353990.com | www.xcw866.com | www.348077.com | www.357803.com | www.322918.com | www.196046.com | www.89894n.com | www.60108e.com | www.07163n.com |