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      當前位置:首頁 > 智慧健康列表 > 光生物學與技術 > 詳細信息
      組織諧波成像的模擬研究
      來源: | 作者: | 發布時間:2014-4-15 18:00:15

      組織諧波成像的模擬研究
      余錦華1,2,汪源源1,2
      (1. 復旦大學專用集成電路與系統國家重點實驗室,上海 200433;2. 復旦大學電子工程系,上海 200433)
      摘要:提出組織諧波成像的模擬算法,研究諧波在組織中的產生、變化規律。通過對線性波動方程的擴展,將非線性和弛豫衰減引入到波動方程的建立中;采用帶吸收邊界條件的時域有限差分法求解非線性波動方程,在此基礎上實現對組織諧波成像過程的模擬。所建立模型能有效模擬聲波在組織中傳播的反射、散射現象,及二次及高次諧波的產生過程。通過對典型組織的模擬,得到了基、諧波在組織中的傳播變化規律,生成的模擬圖像也驗證了諧波成像對提高超聲圖像分辨率的有效性。
      關鍵詞:組織諧波成像;模擬;聲波波動方程;時域有限差分
      中圖分類號:TB553
      Simulation Study of the Tissue Harmonic Imaging

      YU Jinhua1,2, WANG Yuanyuan1,2
      (1. National Key Laborary of ASCI and System of Fudan University, ShangHai 200433;2. Department of Electronic Engineering,Fudan University, ShangHai 200433)
      Abstract: To study the generation and variation tendency of harmonic waves in tissues, a simulation method is proposed for the tissue-harmonic imaging. The linear acoustic wave equations are expanded, and the nonlinearity and relaxation attenuations are introduced into the wave equations. The finite-difference-time-domain with the absorbing boundary condition is used to solve the nonlinear acoustic wave equations. Simulation of the tissue-harmonic imaging is thereafter achieved. The implemented simulation model is able to effectively simulate the reflection and scattering phenomenon of the acoustic waves in tissues, and also the generation of second and high-order harmonics. Typical tissues are simulated to obtain the  ransmitting and variation tendencies of the fundamental- and harmonic-waves in tissues. The generated simulation images prove the efficiency of the harmonic imaging in the resolution improvement of ultrasound images.
      Keywords: tissue-harmonic imaging; simulation; acoustic wave equation; finite-differencetime-domain

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