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      當前位置:首頁 > 智慧健康列表 > 微循環研究 > 詳細信息
      基于GPU的光柵相襯成像的相位恢復和CT重建
      來源: | 作者: | 發布時間:2014-4-15 18:36:04

      基于GPU的光柵相襯成像的相位恢復和CT重建
      陳曉慶1,王宇杰2,孫建奇3
      基金項目:教育部博士點基金新教師類項目基金(20100073120004);國家973項目基金(2010CB834300) 作者簡介:陳曉慶(1989-),女,碩士研究生,光柵相襯成像系統的相位恢復和CT重建算法研究 通信聯系人:孫建奇(1981-), 男, 助理研究員,博士, 同步輻射醫學影像.

      (1. 上海交通大學生物醫學工程學院,上海 200240; 5 2. 上海交通大學物理與天文系,上海 200240; 3. 上海交通大學生物醫學工程學院, 上海 200240)
      摘要:在醫學圖像領域中,區分吸收系數相近的物質的要求越來越高,同時也越來越普遍,如血管和組織,血管和腫瘤等。相比傳統基于吸收信息進行重建的方法,光柵相襯成像的方10 法利用不同物質相位信息變化更為明顯的特點對樣品進行重建獲得了更好的圖像質量。但隨之而來的是,光柵相襯成像產生了更多的實驗數據需要處理。通過對GPU的CUDA C并行編程,將相襯成像數據在GPU內核函數中進行相位恢復和濾波反投影重建取得了既快又好的實驗結果。光柵相襯成像實驗結果顯示出了很好的空間分辨率和對比度分辨率,尤其是針對弱吸收的軟組織,跟傳統的吸收成像相比,具有更強烈的對比度和更清晰的組織結構,在以后15 的應用過程中能夠幫助醫生更準確的找準病灶并分析。其次,相比于標準C程序實現CT重建,基于GPU的CUDA C的光柵相襯成像CT重建程序獲得了比較明顯的加速比,尤其是實驗數據增多的情況下,加速比的增長趨勢也變得更為明顯和突出。
      關鍵詞:生物醫學工程;光柵相襯成像;GPU并行加速;濾波反投影 20
      中圖分類號:R318.6
      GPU-Based Phase Retrieval and CT Reconstruction for Differential X-Ray Phase Contrast Imaging
      CHEN Xiaoqing1, WANG Yujie2, SUN Jiaoqi3 25
      (1. School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai 200240; 2. School of Physics and Astronomy, Shanghai Jiao Tong University, Shanghai 200240; 3. School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai, 200240)
      Abstract: In this paper, compared with the conventional absorption imaging, the differential X-ray phase contrast imaging shows a higher spatial resolution and contrast resolution on reconstruction 30 images especially when dealing with the samples with low attenuation coefficient such as the vessels, soft tissues and so on. The grating based phase contrast system has been widely used with its advantages on the wide range of sample selections and independence with the crystal compared with the propagation-based phase contrast imaging and the diffraction enhancement imaging. However, large data acquired from the phase-stepping method in every projection angle consumes 35 the time of reconstruction. Graphic Processing Unit (GPU) has a wide advantage on parallel computing with multiprocessors and thousands of threads. This paper introduced the CUDA C programming model based on GPU to accelerate the phase retrieval and FBP algorithm on grating phase contrast system. According to the different size of data, the CUDA C program shows a different speed-up over the standard C program on the same Visual Studio 2010 platform. 40 Meanwhile, the speed-up ratio shows an increasing tendency when the size of data increases
      Key words: Biomedical Engineering; Grating-based phase-contrast imaging ;parallel computing based on GPU, Filtered Back Projection

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